Spencer G R, Prothero D L, Dawkins P D, Akehurst A C, Turner D R
Br J Surg. 1982 Apr;69(4):191-2. doi: 10.1002/bjs.1800690404.
The tumors of 61 patients suffering from primary adenocarcinoma of the breast were assayed for oestrogen receptors (ER), using the dextran-coated charcoal method. A statistically significant relationship (P less than 0.05) was found to exist between ER status and the histological grade of the tumour. No relationship was found between ER status and either tumour size or the pathological state of the axillary lymph nodes. It is concluded that it is a practical proposition to establish an ER assay service in a district general hospital, with subsequent benefits for the individual patient.
采用葡聚糖包被活性炭法，对61例原发性乳腺癌患者的肿瘤进行雌激素受体（ER）检测。结果发现，ER状态与肿瘤组织学分级之间存在统计学显著相关性（P<0.05）。未发现ER状态与肿瘤大小或腋窝淋巴结病理状态之间存在相关性。得出结论，在地区综合医院建立ER检测服务是一项切实可行的提议，对个体患者有后续益处。
