Isono K, Onoda S, Ishikawa T, Sato H, Nakayama K
Cancer. 1982 May 15;49(10):2173-9. doi: 10.1002/1097-0142(19820515)49:10<2173::aid-cncr2820491032>3.0.co;2-z.
Statistics on the causes for deaths of 638 patients operated on in our department for resection of cancer of the intrathoracic esophagus (squamous cell carcinoma) during the period from 1959-1979 showed that the major causes for direct operative deaths were pyothorax, pulmonary complications, failure of the sutures, and postoperative hemorrhage. Among operation survivors, recurrence was the most frequent cause of death, responsible for the deaths of as many as 80% of less-than-five year survivors; and recurrence in the cervical, supraclavicular fossa, and superior mediastinal lymph nodes and that in the other organs were the frequent causes for the deaths of two- to three-year survivors. Pulmonary complications were the causes for the deaths of 50%, and recurrence for the deaths of 30% of five- to ten-year survivors. Recurrence in the digestive organs other than the esophagus and cardiovascular diseases were the frequent causes for the deaths of more-than ten-year survivors, while none of these survivors died of recurrence.
对1959年至1979年期间在我科接受胸段食管癌(鳞状细胞癌)切除术的638例患者的死亡原因进行统计,结果显示直接手术死亡的主要原因是脓胸、肺部并发症、缝合失败和术后出血。在手术存活者中,复发是最常见的死亡原因,多达80%的五年内存活者死于复发;而颈部、锁骨上窝和上纵隔淋巴结复发以及其他器官复发是两到三年存活者死亡的常见原因。肺部并发症是50%的五到十年存活者的死亡原因,复发是30%的此类存活者的死亡原因。食管以外的消化器官复发和心血管疾病是十年以上存活者死亡的常见原因,而这些存活者均无死于复发者。