Yoshioka S, Saitoh S, Fujisawa T, Fujimori A, Takatani O, Funabashi M
Clin Chem. 1982 Jun;28(6):1283-6.
1-Deoxyglucose (1,5-anhydroglucitol), a metabolite related to diabetes mellitus, was identified in human plasma by gas-liquid chromatography and by gas-liquid chromatography/mass spectrometry. Plasma polyols were accurately determined with a gas-liquid chromatograph equipped with an all-glass capillary column. The plasma content of 1-deoxyglucose in healthy persons varies with age. Although the precise physiological role of 1-deoxyglucose remains obscure, the method described here for determining the minor polyol components of plasma, as well as the findings of 1-deoxyglucose in the plasma of healthy subjects, may be useful for investigating the metabolic roles of 1-deoxyglucose.
1-脱氧葡萄糖（1,5-脱水葡萄糖醇）是一种与糖尿病相关的代谢物，通过气液色谱法和气液色谱/质谱法在人体血浆中被鉴定出来。使用配备全玻璃毛细管柱的气液色谱仪准确测定血浆多元醇。健康人血浆中1-脱氧葡萄糖的含量随年龄变化。尽管1-脱氧葡萄糖的确切生理作用仍不清楚，但本文所述的测定血浆中微量多元醇成分的方法以及健康受试者血浆中1-脱氧葡萄糖的检测结果，可能有助于研究1-脱氧葡萄糖的代谢作用。
