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中国新生儿脐血高甘油三酯血症:胎儿窘迫的一个指标。

Cord blood hypertriglyceridemia in Chinese newborns: an index of fetal distress.

作者信息

Chow S N, Chen H Y, Ouyang P C

出版信息

Int J Biol Res Pregnancy. 1982;3(1):33-7.

PMID:7076334
Abstract

Cord serum triglyceride concentrations in 214 Chinese newborns were measured at birth with the Hitachi Model 716 autoanalyzer using the G-3-PDH UV end point method. The mean and the 95th percentile value in a normal population of 100 newborns were found to be 28 mg/100 ml and 48 mg/100 ml, respectively. Using 48 mg/100 (P95) as a cut-off point, maternal-fetal factors were evaluated in 35 hypertriglyceridemic and 35 normotriglyceridemic newborns. A significant association was demonstrated between high cord serum triglyceride levels and toxemia, overterm, meconium-stained amniotic fluid, deceleration of fetal heart rate, intrauterine growth retardation, low one-minute Apgar score (less than or equal to 7), and low umbilical arterial pH (less than 7.20). These findings pointed out that cord serum hypertriglyceridemia was an index of fetal distress and associated with many unfavorable intrauterine conditions. They also suggested that hypertriglyceridemia might be related to the activated sympathetic nervous system and the enhanced release of catecholamines.

摘要

采用日立716型自动分析仪,运用G-3-PDH紫外终点法,对214名中国新生儿出生时的脐血甘油三酯浓度进行了测定。在100名正常新生儿群体中,其平均值及第95百分位数分别为28mg/100ml和48mg/100ml。以48mg/100(P95)作为切点,对35名高甘油三酯血症新生儿和35名正常甘油三酯血症新生儿的母婴因素进行了评估。结果显示,脐血甘油三酯水平升高与子痫前期、过期产、羊水胎粪污染、胎儿心率减速、宫内生长迟缓、1分钟阿氏评分低(小于或等于7分)以及脐动脉血pH值低(小于7.20)之间存在显著关联。这些发现指出,脐血高甘油三酯血症是胎儿窘迫的一个指标,且与许多不良宫内情况相关。研究还表明,高甘油三酯血症可能与交感神经系统激活及儿茶酚胺释放增加有关。

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Cord blood hypertriglyceridemia in Chinese newborns: an index of fetal distress.中国新生儿脐血高甘油三酯血症:胎儿窘迫的一个指标。
Int J Biol Res Pregnancy. 1982;3(1):33-7.
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Int J Prev Med. 2013 Jul;4(7):755-60.