Khayat A, Dencker L
Int J Biol Res Pregnancy. 1982;3(1):38-46.
The placental transport of mercury in pregnant mice and its localization in the embryo and fetus from early organogenesis through the whole fetal period was studied by whole-body autoradiography and gamma counting. Metallic mercury (203Hg0) (after inhalation) was compared to inorganic 203HgCl2 (after i.v. injection). Hg0 appears to be oxidized to Hg2+ in the fetal tissues and Hg0 inhalation results in about 4-fold higher fetal mercury concentration than Hg2+ injection (9.9 versus 2.4% gram dose per gram tissue). Preadmission to the dams with ethanol or aminotriazole resulted in higher fetal concentrations (especially in the liver) of mercury after inhalation of Hg0 but not after injection of Hg2+. A high placental concentration and accumulation in the corpora lutea of mercury after Hg0 inhalation should be also noted.
通过全身放射自显影和伽马计数研究了汞在妊娠小鼠体内的胎盘转运及其在胚胎和胎儿中的定位，从早期器官发生到整个胎儿期。将金属汞（203Hg0）（吸入后）与无机203HgCl2（静脉注射后）进行了比较。Hg0似乎在胎儿组织中被氧化为Hg2+，吸入Hg0导致的胎儿汞浓度比注射Hg2+高约4倍（每克组织中分别为9.9%和2.4%克剂量）。在母鼠中预先给予乙醇或氨基三唑，在吸入Hg0后会导致胎儿汞浓度升高（尤其是在肝脏中），但注射Hg2+后则不会。还应注意吸入Hg0后胎盘汞浓度高以及在黄体中的积累。
