Wermeille M M, Huber G A
J Chromatogr. 1982 Mar 12;228:187-94. doi: 10.1016/s0378-4347(00)80431-4.
A simple method for the determination of dimethindene down to a concentration of 10 ng/ml in human urine and serum is described. After the addition of an internal standard, the dimethindene is extracted as the free base with pentane. Measurements are made directly by gas--liquid chromatography using a flame ionization detector.
本文描述了一种测定人尿和血清中二甲茚定浓度低至10 ng/ml的简单方法。加入内标后,二甲茚定以游离碱形式用戊烷萃取。采用火焰离子化检测器通过气液色谱法直接进行测定。