Bergeder H D, Rink H, Hockwin O
Klin Monbl Augenheilkd. 1982 Jan;180(1):13-6. doi: 10.1055/s-2008-1055003.
X-rays are known to be a true cataractogenic agent. Since they can be accurately dosed and directed they are particularly suitable for inducing experimental cataracts. By means of ionizing rays, lesions are induced in various lens segments. Both the extent of the damage as well as the latency period until it becomes manifest are highly age-dependent. Since lens changes effected by ionizing rays are in many respects, similar to age-related changes, experimental cataracts induced by X-rays provide suitable models for investigating processes involved in the multifactorial genesis of senile cataract.
X射线是一种公认的真正致白内障因子。由于其剂量和照射方向可以精确控制,因此特别适合用于诱发实验性白内障。通过电离射线,可以在晶状体的不同部位诱发损伤。损伤的程度以及损伤显现出来的潜伏期都高度依赖于年龄。由于电离射线引起的晶状体变化在很多方面与年龄相关变化相似,因此X射线诱发的实验性白内障为研究老年性白内障多因素发病机制中涉及的过程提供了合适的模型。