Bixler E O, Kales A, Vela-Bueno A, Jacoby J A, Scarone S, Soldatos C R
Res Commun Chem Pathol Pharmacol. 1982 Apr;36(1):129-40.
The presence of nocturnal myoclonus (NM) and nocturnal myoclonic activity (NMA) was assessed in the sleep laboratory in 100 subjects without any complaint of sleep disturbance. Subjects were included only if they were physically and mentally healthy and not using any medication. The subject sample was selected to have a representative proportion of women and men and a wide age distribution. Six percent of the subjects met the clinical criteria for NM, and five percent had NMA. Thus, either NM or NMA was noted in 11 percent of the total sample. The prevalence of NM or NMA was slightly higher in men than in women and positively and significantly correlated with increasing age. No relationship was found between the presence of NM or NMA and weight, smoking, or the consumption of caffeinated beverages. When the amount of each sleep stage was controlled for, myoclonic activity occurred most frequently during stage 2 sleep. The degree of sleep disturbance related to myoclonic activity was minimal, with the mean total duration of both types of myoclonic activity per subject-night being only about six minutes. In addition, only about 10 percent of the events were related to EEG arousals.
在睡眠实验室中，对100名无任何睡眠障碍主诉的受试者进行了夜间肌阵挛（NM）和夜间肌阵挛活动（NMA）评估。仅纳入身心健康且未服用任何药物的受试者。受试者样本的选择确保了男女比例具有代表性且年龄分布广泛。6%的受试者符合NM的临床标准，5%有NMA。因此，在总样本的11%中发现了NM或NMA。NM或NMA的患病率男性略高于女性，且与年龄增长呈正相关且具有显著性。未发现NM或NMA的存在与体重、吸烟或含咖啡因饮料的摄入之间存在关联。当对每个睡眠阶段的时长进行控制后，肌阵挛活动最常发生在睡眠2期。与肌阵挛活动相关的睡眠障碍程度极小，每位受试者每晚两种类型肌阵挛活动的平均总时长仅约6分钟。此外, 仅约10%的事件与脑电图觉醒有关。
