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[使用“Steritest”仪器检测抗生素制剂的无菌性]

[Use of the "Steritest" apparatus for testing the sterility of antibiotic preparations].

作者信息

Shilova S V, Braginskaia P S, Chaĭkovskaia S M, Massot A, Lemonie J

出版信息

Antibiotiki. 1978 Oct;23(10):879-82.

PMID:707996
Abstract

The efficiency of determining microbial contamination of artificially infected preparations of 8 antibiotics in ampoules and bottles and erythromycin eye ointment with the use of apparatus "Steritest" and "Millipore" was compared. It was found that "Steritest" had a number of advantages as compared to "Millipore" because of elimination of operations for preparing the apparatus for the assay, which prevented contamination of the apparatus with microorganisms from the environment. The time required for the assay with the use of "Steritest" was 2 times shorter and the amount of the tioglycol medium was 2 times lower.

摘要

比较了使用“Steritest”和“Millipore”仪器测定安瓿瓶和瓶装8种抗生素以及红霉素眼膏人工感染制剂微生物污染的效率。结果发现,与“Millipore”相比,“Steritest”具有许多优势,因为它无需进行仪器准备操作,从而避免了仪器被环境中的微生物污染。使用“Steritest”进行检测所需的时间缩短了一半,硫代乙醇酸盐培养基的用量减少了一半。

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