Omer E F, El Sheikh F S, Khalil I A
Trop Doct. 1982 Apr;12(2):61-2. doi: 10.1177/004947558201200205.
2201 blood donors and 199 patients with sexually transmitted diseases (STD) were tested with the Venereal Disease Research Laboratory (VDRL) and the fluorescent treponemal antibody-absorption (FTA-ABS) tests. The VDRL test was found positive in 30 (1.36%) of the blood donors and 11 (5.5%) of the patients. Syphilis was confirmed by FTA-ABS test in one patient (0.5%) but not in blood donors. The biological false positive (BFP) reactions were 1.36% in blood donors and 5.0% in control patients. The place of VDRL test as a screening test for syphilis and the low rate of its seroreactivity among blood donors was discussed. The BFP reactions were reviewed to assist in the interpretation of the VDRL test which was evaluated on the basis of the control specimens. It was concluded that syphilis should be excluded before blood is transfused and the VDRL test should remain the screening test of choice in the blood transfusion service.
对2201名献血者和199名性传播疾病（STD）患者进行了性病研究实验室（VDRL）试验和荧光密螺旋体抗体吸收（FTA-ABS）试验。结果发现，VDRL试验在30名（1.36%）献血者和11名（5.5%）患者中呈阳性。通过FTA-ABS试验确诊一名患者患有梅毒（0.5%），但在献血者中未发现梅毒患者。献血者的生物学假阳性（BFP）反应率为1.36%，对照患者为5.0%。讨论了VDRL试验作为梅毒筛查试验的地位以及献血者中其血清反应性较低的情况。回顾了BFP反应，以协助解释基于对照标本评估的VDRL试验。得出的结论是，输血前应排除梅毒，VDRL试验应仍然是输血服务中的首选筛查试验。
