Aber R C, Wennersten C, Moellering R C
Antimicrob Agents Chemother. 1978 Sep;14(3):483-7. doi: 10.1128/AAC.14.3.483.
Antimicrobial susceptibility patterns of 28 clinical isolates of Flavobacterium sp. were determined by standard disk diffusion technique and by antimicrobial dilution in agar. Rifampin, clindamycin, trimethoprim-sulfamethoxazole, cefoxitin, and vancomycin are among the antimicrobial agents which may be clinically useful to treat infections caused by flavobacteria. All 28 isolates were resistant to erythromycin with minimal inhibitory concentrations of 32 mug/ml or more. Currently recommended interpretive zones of inhibition by disk diffusion did not reliably predict antimicrobial susceptibility of the 28 flavobacteria isolates when compared with the agar dilution technique, and, therefore, a more direct measurement of minimal inhibitory or bactericidal concentration is recommended.
采用标准纸片扩散法和琼脂稀释抗菌法测定了28株黄杆菌临床分离株的抗菌药敏模式。利福平、克林霉素、甲氧苄啶-磺胺甲恶唑、头孢西丁和万古霉素等抗菌药物可能在临床上用于治疗由黄杆菌引起的感染。所有28株分离株对红霉素耐药，最低抑菌浓度为32μg/ml或更高。与琼脂稀释法相比，目前推荐的纸片扩散法抑菌解释范围不能可靠地预测这28株黄杆菌分离株的抗菌药敏情况，因此，建议采用更直接的最低抑菌或杀菌浓度测定方法。
