Christopherson W M, Alberhasky R C, Connelly P J
Am J Clin Pathol. 1982 May;77(5):534-40. doi: 10.1093/ajcp/77.5.534.
Forty-six patients with papillary carcinoma of the endometrium were studied. Forty-five were followed for at least five years or until death, and 41 were followed for 10 years. The remaining patient was alive at four years. The survival rate was 51.1% at five years and 46.3% at 10 years. At five years one-third had died of their disease. The median age at time of diagnosis was 63 years, and the age at diagnosis was an important determinant of survival. None of the seven black women survived for five years. Tumor grade was an important predictor of the course of disease and nuclear grading was a significantly more accurate indicator than was the histologic grading of the World Health Organization. Papillary carcinoma should be distinguished from the papillary type of clear cell carcinoma of the endometrium. While it has a somewhat better prognosis than mixed adenosquamous carcinoma or clear cell carcinoma, it appears to be more aggressive with a lower survival rate and higher rate of death from disease than the usual type of endometrial adenocarcinoma or adenoacanthoma.
对46例子宫内膜乳头状癌患者进行了研究。45例患者随访至少5年或直至死亡，41例患者随访10年。其余1例患者在4年时仍存活。5年生存率为51.1%，10年生存率为46.3%。5年时三分之一的患者死于该病。诊断时的中位年龄为63岁，诊断年龄是生存的重要决定因素。7名黑人女性中无一例存活5年。肿瘤分级是疾病进程的重要预测指标，核分级比世界卫生组织的组织学分级是一个明显更准确的指标。子宫内膜乳头状癌应与子宫内膜透明细胞癌的乳头状类型相鉴别。虽然它的预后比混合性腺鳞癌或透明细胞癌稍好，但它似乎更具侵袭性，生存率较低，死于疾病的比率高于子宫内膜腺癌或腺棘皮瘤的常见类型。
