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兔乳腺脂肪酸合成酶的分子量和亚基大小

Molecular weight and subunit size of rabbit mammary-gland fatty acid synthetase.

作者信息

Grunnet I, Knudsen J

出版信息

Biochem J. 1978 Sep 1;173(3):929-33. doi: 10.1042/bj1730929.

DOI:10.1042/bj1730929
PMID:708381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1185861/
Abstract
  1. The molecular weights of fatty acid synthetases isolated from lactating rabbit, rat, cow and goat mammary glands were estimated by sucrose gradient centrifugation and compared by chromatography on Sepharose 6B. 2. The values obtained for all four enzymes were in the same range (0.40 X 10(6)-0.55 X 10(6)) as that found for other mammalian and avian fatty acid synthetases. The molecular weight found for the rabbit mammary enzyme therefore differs from published values of approx. 0.9 X 10(6). 3. The molecular weights of the subunits of these four synthetases were 225000-242000. Again, the value for the rabbit mammary enzyme differs from published values.
摘要
  1. 通过蔗糖梯度离心法估算了从泌乳兔、大鼠、牛和山羊乳腺中分离出的脂肪酸合成酶的分子量,并通过在琼脂糖6B上的色谱法进行了比较。2. 所有四种酶获得的值与其他哺乳动物和禽类脂肪酸合成酶的值在相同范围内(0.40×10⁶ - 0.55×10⁶)。因此,兔乳腺酶的分子量与已发表的约0.9×10⁶的值不同。3. 这四种合成酶亚基的分子量为225000 - 242000。同样,兔乳腺酶的值与已发表的值不同。
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a17/1185861/cd1b49c17f22/biochemj00481-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a17/1185861/cd1b49c17f22/biochemj00481-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a17/1185861/cd1b49c17f22/biochemj00481-0233-a.jpg

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引用本文的文献

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Biochem J. 1983 Jan 1;209(1):215-22. doi: 10.1042/bj2090215.
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Acyl-CoA-binding protein from cow. Binding characteristics and cellular and tissue distribution.

本文引用的文献

1
A method for determining the sedimentation behavior of enzymes: application to protein mixtures.一种测定酶沉降行为的方法:应用于蛋白质混合物
J Biol Chem. 1961 May;236:1372-9.
2
Yeast alcohol dehydrogenase: molecular weight, coenzyme binding, and reaction equilibria.酵母乙醇脱氢酶:分子量、辅酶结合及反应平衡
J Biol Chem. 1954 Mar;207(1):225-44.
3
The effects of nutritional and hormonal factors on the fatty acid synthetase level of rat liver.营养和激素因素对大鼠肝脏脂肪酸合成酶水平的影响。
来自牛的酰基辅酶A结合蛋白。结合特性以及细胞和组织分布。
Biochem J. 1987 Dec 15;248(3):709-14. doi: 10.1042/bj2480709.
4
Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase.泌乳兔乳腺中中链脂肪酸的合成。中链酰基硫酯水解酶的细胞内浓度及特异性。
Biochem J. 1979 Aug 1;181(2):267-74. doi: 10.1042/bj1810267.
J Biol Chem. 1969 Aug 25;244(16):4510-6.
4
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳测定分子量的可靠性。
J Biol Chem. 1969 Aug 25;244(16):4406-12.
5
Comparative studies of the rat and pigeon liver fatty acid synthetases.大鼠和鸽子肝脏脂肪酸合成酶的比较研究。
Arch Biochem Biophys. 1968 Jul;126(1):141-54. doi: 10.1016/0003-9861(68)90568-7.
6
Fatty acid biosynthesis. V. Purification and characterisation of fatty acid synthetase from lactating-rabbit mammary gland.脂肪酸生物合成。V. 泌乳兔乳腺脂肪酸合成酶的纯化与特性鉴定。
Biochim Biophys Acta. 1970 Sep 8;210(3):371-87. doi: 10.1016/0005-2760(70)90033-0.
7
Fatty acid synthetase from lactating rat mammary gland. I. Isolation and properties.来自泌乳大鼠乳腺的脂肪酸合成酶。I. 分离与性质
J Biol Chem. 1970 Jun;245(12):3209-17.
8
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
9
Stabilization and physicochemical properties of the fatty acid synthetase of chicken liver.鸡肝脂肪酸合成酶的稳定性及物理化学性质
Biochemistry. 1970 Jan 20;9(2):239-45. doi: 10.1021/bi00804a008.
10
Fatty acid synthetase from lactating rat mammary gland. 3. Dissociation and reassociation.来自泌乳大鼠乳腺的脂肪酸合成酶。3. 解离与重新结合。
J Biol Chem. 1971 Nov;246(21):6428-35.