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弓形虫、弓蛔虫与癫痫

Toxoplasma, Toxocara, and epilepsy.

作者信息

Critchley E M, Vakil S D, Hutchinson D N, Taylor P

出版信息

Epilepsia. 1982 Jun;23(3):315-21. doi: 10.1111/j.1528-1157.1982.tb06197.x.

DOI:10.1111/j.1528-1157.1982.tb06197.x
PMID:7084141
Abstract

The presence of positive antibody titres to Toxoplasma and Toxocara in an adult epileptic population has been examined in relation to other observations of aetiological importance. With Toxoplasma, and more particularly with Toxocara, a higher incidence of positive antibody titres was recorded than in nonepileptic populations. Comparison with previous studies in childhood epilepsy indicate that the incidence of positive titres increased with age throughout adult life. Despite attention to the age of onset of epilepsy, presumed aetiological factors, and electroencephalographic and clinical observations, no causal relationship between parasitic infection and the aetiology of epilepsy was established.

摘要

针对成年癫痫患者群体中弓形虫和弓蛔虫抗体滴度呈阳性的情况,已结合其他具有病因学重要性的观察结果进行了研究。对于弓形虫,尤其是弓蛔虫,记录到的抗体滴度阳性发生率高于非癫痫患者群体。与先前关于儿童癫痫的研究相比,表明在整个成年期,抗体滴度阳性的发生率随年龄增长而增加。尽管关注了癫痫的发病年龄、推测的病因因素以及脑电图和临床观察,但未确立寄生虫感染与癫痫病因之间的因果关系。

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