大鼠脑亚细胞颗粒中双唾液酸神经节苷脂GDla在发育过程中的情况。
Disialoganglioside GDla of rat brain subcellular particles during development.
作者信息
Yusuf H K, Dickerson J W
出版信息
Biochem J. 1978 Aug 15;174(2):655-7. doi: 10.1042/bj1740655.
Abstract
The increase observed in the amount of the disialoganglioside GDlof the rat cerebrum during development between 21 and 81 days of age accounted for nearly 40% of the overall increase in total ganglioside in the tissue during the same period. Subcellular fractionation showed the microsomal fraction to contribute by far the most towards this increase in Cerebral ganglioside GDla. It is suggested that microsomal ganglioside GDla may serve as a marker for dendritic arborization in the rat cerebrum.
摘要
在21至81日龄大鼠大脑发育过程中观察到的二唾液酸神经节苷脂GDla量的增加，占同期该组织中总神经节苷脂总体增加量的近40%。亚细胞分级分离显示，微粒体部分对大脑神经节苷脂GDla的这种增加贡献最大。有人提出，微粒体神经节苷脂GDla可能作为大鼠大脑中树突分支的一个标志物。
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