Ursell P C, Albala A, Fenoglio J J
Hum Pathol. 1982 Jul;13(7):677-9. doi: 10.1016/s0046-8177(82)80015-4.
This report is the first to document the definitive diagnosis of acute rheumatic carditis by endomyocardial biopsy. An adolescent girl with mitral regurgitation and biventricular congestive heart failure thought to be secondary to rheumatic heart disease was admitted to the hospital for mitral valve replacement. An endomyocardial biopsy performed at cardiac catheterization demonstrated and Aschoff's body in the endocardium and thus confirmed a clinical suspicion of active carditis. Following a course to steroids, the mitral valve was replaced. The surgically excised valve showed gross and microscopic features of acute and chronic valvulitis consistent with rheumatic endocarditis.
本报告首次记录了通过心内膜活检对急性风湿性心脏炎进行明确诊断的病例。一名患有二尖瓣反流和双心室充血性心力衰竭的青春期女孩，病因被认为是风湿性心脏病继发，因二尖瓣置换入院。在心脏导管插入术时进行的心内膜活检显示心内膜中有阿绍夫小体，从而证实了临床对活动性心脏炎的怀疑。经过类固醇治疗后，进行了二尖瓣置换。手术切除的瓣膜显示出与风湿性心内膜炎一致的急慢性瓣膜炎的大体和微观特征。
