King R J, Barnes D M, Hawkins R A, Leake R E, Maynard P V, Roberts M M
Br J Cancer. 1978 Sep;38(3):428-30. doi: 10.1038/bjc.1978.224.
The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours.
5个不同实验室对常见乳腺肿瘤的可溶性雌激素受体含量进行了测定，每个实验室都采用各自的检测方法。在雌激素受体样本是阳性还是阴性的判断上达成了良好的一致。实验室之间的定性差异可以通过检测介质中硫醇试剂含量的差异以及匀浆方法来解释。针对乳腺肿瘤受体常规检测中涉及的一些因素提出了建议。
