原发性胆汁性肝硬化：肝外恶性肿瘤的发病率增加？
Primary biliary cirrhosis: an increased incidence of extrahepatic malignancies?
作者信息
Mills P R, Boyle P, Quigley E M, Birnie G G, Jarrett F, Watkinson G, MacSween R N
出版信息
J Clin Pathol. 1982 May;35(5):541-3. doi: 10.1136/jcp.35.5.541.
Abstract
In a retrospective review of 85 patients with primary biliary cirrhosis (PBC), 10 (11.8%) were noted to have extrahepatic malignant neoplasm. In seven female patients the tumour developed within a mean of 3.5 yr after the clinical onset of PBC. This observed number of tumours, 3.5 times more common than the expected age-adjusted incidence, was statistically significant at the 0.5% level.
摘要
在一项对85例原发性胆汁性肝硬化（PBC）患者的回顾性研究中，发现10例（11.8%）患有肝外恶性肿瘤。在7例女性患者中，肿瘤在PBC临床发病后平均3.5年出现。观察到的肿瘤数量比预期的年龄调整发病率高3.5倍，在0.5%水平上具有统计学意义。
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