人类白细胞抗原（HLA）抗原与黏液性水肿

HLA antigens and myxedema.

作者信息

Májský A, Feix C

出版信息

Tissue Antigens. 1977 Aug;10(2):119-20. doi: 10.1111/j.1399-0039.1977.tb01127.x.

DOI:10.1111/j.1399-0039.1977.tb01127.x

Abstract

In 22 cases of myxedema 22 HLA-A and B antigens were typed. In six out of eight patients with a history of subacute thyroiditis Bw35 antigen was demonstrated, while in none of 14 patients free from this disease in anamnesis could this antigen be found. This difference is statistically significant, and suggests classifying of myxedema patients into two groups according to pathogenesis of the disease.

摘要

对22例黏液性水肿患者进行了22种HLA - A和B抗原分型。在8例有亚急性甲状腺炎病史的患者中，有6例显示出Bw35抗原，而在14例既往无此病的患者中均未发现该抗原。这种差异具有统计学意义，提示可根据疾病的发病机制将黏液性水肿患者分为两组。