Stevens J R, Livermore A
J Neurol Neurosurg Psychiatry. 1982 May;45(5):385-95. doi: 10.1136/jnnp.45.5.385.
In an attempt to detect electroencephalographic (EEG) changes associated with characteristic clinical signs and symptoms of schizophrenia, power spectra were derived from scalp EEGs of schizophrenic patients recorded by telemetry during free behaviour on their psychiatric wards. Power spectra from EEG epochs coincident with psychomotor blocking, stereotyped automatism or hallucinations were compared with spectra derived during periods of relatively normal behaviour, during performance of specific tasks and spectra from control subjects. Ramp spectra, characterised by a smooth decline in power from lowest to highest frequencies, previously found in conjunction with subcortical spike activity of epilepsy were not found in any control subject, but appeared in spectra from schizophrenic patients during catatonic episodes, hallucinatory periods and visual checking. Schizophrenic patients also had more slow activity and less alpha activity in their EEGs than normal control subjects.
为了检测与精神分裂症特征性临床体征和症状相关的脑电图（EEG）变化，对精神科病房中通过遥测记录的精神分裂症患者在自由活动期间的头皮脑电图进行功率谱分析。将与精神运动阻滞、刻板自动症或幻觉同时出现的脑电图时段的功率谱，与相对正常行为期间、特定任务执行期间的功率谱以及对照组受试者的功率谱进行比较。斜坡谱的特征是功率从最低频率到最高频率平滑下降，先前发现其与癫痫的皮层下棘波活动有关，在任何对照组受试者中均未发现，但在紧张症发作、幻觉期和视觉检查期间精神分裂症患者的频谱中出现。与正常对照组相比，精神分裂症患者脑电图中的慢波活动更多，α波活动更少。
