Bregman B S, Goldberger M E
Science. 1982 Aug 6;217(4559):553-5. doi: 10.1126/science.7089581.
Spinal cord damage in neonatal cats has different effects on different spinal pathways. Corticospinal projections exhibit anatomical plasticity, forming an aberrant pathway that bypasses the lesion. In contrast, brainstem-spinal pathways undergo massive retrograde degeneration. Neither of these responses occurs in adult cats. Sparing of motor function is found in cats operated on as neonates but not in cats operated on as adults, and appears to depend on the plasticity of the corticospinal tract.
新生猫的脊髓损伤对不同的脊髓通路有不同影响。皮质脊髓投射表现出解剖学可塑性，形成一条绕过损伤部位的异常通路。相比之下，脑干 - 脊髓通路则会发生大量逆行性变性。这两种反应在成年猫中均不会出现。在新生时接受手术的猫中发现有运动功能保留，但成年时接受手术的猫则没有，并且这似乎取决于皮质脊髓束的可塑性。
