Sidd R J, Fine S L, Owens S L, Patz A
Am J Ophthalmol. 1982 Jul;94(1):44-8. doi: 10.1016/0002-9394(82)90189-1.
Of 89 patients with idiopathic preretinal gliosis examined between 1970 and 1978, 52 were examined within six months of the onset of symptoms. Forty-seven patients were men and 42 were women; 83 (93%) were more than 50 years old. Initial visual acuities were 6/12 (20/40) or better in 60 of 98 eyes (61%). Nine patients had initial bilateral involvement, and the second eye became involved in one other patient during the follow-up period. Posterior vitreous detachment was present in 59 of the 64 eyes (92%) for which the state of the vitreous had been recorded; 16 of 74 eyes (21%) had fluorescein leakage into the macula. During a mean follow-up period of 31.1 months, the appearance of the fundus remained unchanged in 65 of 72 eyes (90%). Fifty-one of the 72 eyes (71%) had final visual acuities within one line of those recorded at the first examination. Spontaneous improvement of two lines or more occurred in only two patients, accompanied in both cases by an apparent decrease in the severity of the retinal wrinkling. Although these data indicated that idiopathic preretinal gliosis is generally a nonprogressive condition that does not cause serious visual loss, those patients followed up for more than three years did have a small overall decline in visual acuity.
在1970年至1978年间检查的89例特发性视网膜前胶质增生患者中，52例在症状出现后6个月内接受了检查。47例为男性，42例为女性；83例（93%）年龄超过50岁。98只眼中，60只（61%）的初始视力为6/12（20/40）或更好。9例患者初始双侧受累，另有1例患者在随访期间对侧眼受累。在记录了玻璃体状态的64只眼中，59只（92%）存在玻璃体后脱离；74只眼中有16只（21%）荧光素渗漏至黄斑区。在平均31.1个月的随访期内，72只眼中有65只（90%）眼底外观保持不变。72只眼中有51只（71%）的最终视力与首次检查记录的视力相差不超过一行。仅2例患者视力自发提高了两行或更多，且这两例患者视网膜皱襞的严重程度均明显减轻。尽管这些数据表明特发性视网膜前胶质增生通常是一种非进行性疾病，不会导致严重视力丧失，但随访超过三年的患者视力总体上确实有小幅下降。
