Akiba J, Yoshida A, Trempe C L
Eye Research Institute, Boston, MA 02114.
Graefes Arch Clin Exp Ophthalmol. 1991;229(2):101-4. doi: 10.1007/BF00170538.
We retrospectively studied 124 eyes with idiopathic preretinal macular fibrosis to assess the value of fluorescein angiography and vitreous examination for predicting the visual prognosis. During a mean follow-up period of 43 months (range, 12-14 months), the visual acuity of 33 eyes (27%) declined two or more lines from the initial value, although the appearance of the fibrosis remained unchanged in 114 cases (92%). At initial examination, 38 eyes (31%) showed fluorescein leakage into the macula; these eyes were more prone to further visual deterioration than were those without leakage (P less than 0.05). Of 14 eyes with partial vitreous detachment and vitreous traction to the fibrosis, 6 (43%) had a final visual acuity of 20/200 or worse; this proportion was significantly higher than that found either in eyes with no detachment or in those with complete vitreous detachment (P less than 0.05). The presence of fluorescein leakage and/or vitreous traction to the fibrosis may predict worse functional prognosis in eyes with idiopathic preretinal macular fibrosis.
我们对124例特发性黄斑前膜患者进行回顾性研究，以评估荧光素血管造影和玻璃体检查对预测视力预后的价值。在平均43个月（范围12 - 14个月）的随访期内，33只眼（27%）的视力较初始值下降两行或更多行，尽管114例（92%）患者的黄斑前膜外观保持不变。初诊时，38只眼（31%）出现黄斑区荧光素渗漏；这些眼比无渗漏者更易发生视力进一步恶化（P < 0.05）。在14只存在部分玻璃体脱离且玻璃体牵拉黄斑前膜的眼中，6只眼（43%）最终视力降至20/200或更差；这一比例显著高于无玻璃体脱离或完全玻璃体脱离的患者（P < 0.05）。黄斑区荧光素渗漏和/或玻璃体对黄斑前膜的牵拉可能预示特发性黄斑前膜患者的功能预后较差。
