Overturf G D, Rigau-Perez J G, Selzer J, Field R J, Powars D, Pang E J, Uy C, Honig G, Weiss J, Chan L, Portnoy B
Am J Pediatr Hematol Oncol. 1982 Spring;4(1):19-23.
Vaccine reaction data were obtained from 154 patients with sickle cell disease immunized with tetradecavalent pneumococcal polysaccharide vaccine. There was a high rate (70%) of mild reactions, primarily at the site of injection. Fever over 100 degrees F was uncommon and precipitation of symptoms similar to sickling crisis was rare. Development of local reactions was associated with the level of preimmunization pneumococcal antibody titer.
疫苗反应数据来自154名接受十四价肺炎球菌多糖疫苗免疫的镰状细胞病患者。轻度反应发生率较高（70%），主要发生在注射部位。超过100华氏度的发热并不常见，类似镰状细胞危象症状的加重也很少见。局部反应的发生与免疫前肺炎球菌抗体滴度水平有关。
