Pappalardo G, Correnti S, Mobarhan S, Trentino P, Pietropaolo A, Frattaroli F, Castrini G
Ann Surg. 1982 Aug;196(2):149-52. doi: 10.1097/00000658-198208000-00006.
The results of the long-term follow-up of 202 patients with Roux-en-Y hepaticojejunostomy (Roux-en-Y HJ) and 19 with hepaticojejunoduodenostomy (HJD) are reported. The mortality, morbidity, and the incidence of postoperative anastomotic stenosis were comparable in both groups. One hundred forty patients with Roux-en-Y HJ and 19 with HJD were followed with barium meal and endoscopy. An incidence of 5% postoperative duodenal ulcer was noted in the first group, while no ulcer was seen in the patients with HJD. Preoperative and postoperative gastric acid secretion (basal acid secretion and maximal acid secretion) and serum gastrin levels (basal and after protein meal) were measured in 25 cases with Roux-en-Y HJ and 19 with HJD. The serum gastrin levels were similar initially and remained unchanged after surgery in both groups. However, the mean levels of basal and maximal acid output, which was similar before surgery in both groups, increased significantly only in patients who had Roux-en-Y HJ (p less than 0.001). In conclusion, HJD should be adopted as the preferred type of anastomosis in patients with benign pathology and long-life expectancy.
报告了202例行Roux-en-Y肝空肠吻合术(Roux-en-Y HJ)患者和19例行肝空肠十二指肠吻合术(HJD)患者的长期随访结果。两组的死亡率、发病率和术后吻合口狭窄发生率相当。140例行Roux-en-Y HJ的患者和19例行HJD的患者接受了钡餐和内镜检查。第一组术后十二指肠溃疡发生率为5%,而HJD患者未见溃疡。对25例行Roux-en-Y HJ的患者和19例行HJD的患者术前和术后的胃酸分泌(基础胃酸分泌和最大胃酸分泌)以及血清胃泌素水平(基础值和进食蛋白质餐后的值)进行了测量。两组血清胃泌素水平最初相似,术后均保持不变。然而,两组术前相似的基础胃酸分泌量和最大胃酸分泌量的平均水平仅在接受Roux-en-Y HJ的患者中显著升高(p<0.001)。总之,对于良性病变且预期寿命较长的患者,应采用HJD作为首选的吻合方式。