Fleming L W, Stewart W k, Fell G S, Halls D J
Clin Nephrol. 1982 May;17(5):222-7.
In a low water aluminium area ( less than or equal to 0.4 micromoles/1) plasma aluminium levels were normal in 31 non-dialyzed and 7 peritoneally-dialyzed patients unless oral aluminium hydroxide was prescribed. Plasma aluminium levels were above normal in 26 patients on maintenance hemodialysis, but when aluminium hydroxide intake stopped there was a decrease in pre-dialysis plasma aluminium. Poor compliers (indicated by plasma phosphate levels) showed no change. Oral aluminium hydroxide can make a major contribution to plasma aluminium levels in patients with renal failure and should be treated with the same caution as high dialyzate aluminium. Post-dialysis plasma aluminium levels were always higher than pre-dialysis levels both on and off aluminium therapy despite the low dialyzate aluminium concentration. This rise may be due to tissue redistribution.
在低水铝地区（小于或等于0.4微摩尔/升），31名未接受透析的患者和7名接受腹膜透析的患者，除非开具口服氢氧化铝处方，其血浆铝水平正常。26名维持性血液透析患者的血浆铝水平高于正常，但当停止摄入氢氧化铝时，透析前血浆铝水平下降。依从性差的患者（以血浆磷酸盐水平为指标）无变化。口服氢氧化铝对肾衰竭患者的血浆铝水平有重要影响，应与高透析液铝一样谨慎对待。无论是否进行铝治疗，尽管透析液铝浓度较低，但透析后血浆铝水平总是高于透析前水平。这种升高可能是由于组织再分布。
