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99mTc 标记的损伤红细胞显示出异常的骨髓影像。

Unusual bone marrow visualization with 99mTc-damaged erythrocytes.

作者信息

Dolgova-Korubin V, Simova N

出版信息

Eur J Nucl Med. 1982;7(5):240-1. doi: 10.1007/BF00256473.

DOI:10.1007/BF00256473
PMID:7094927
Abstract

A visualization of the bone marrow beside that of the spleen was obtained with 99mTc-labeled N-ethylmaleimide (NEM) damaged erythrocytes in a patient with systemic lupus erythematosus. This phenomenon could be produced both with autologous and homologous red cells. The patient's NEM-damaged erythrocytes given to a healthy patient did not produce a visualization of the marrow. Such an observation was not present in a series of healthy persons and patients with different disorders to whom labeled and damaged erythrocytes were administered, and has not been reported in the literature so far.

摘要

在一名系统性红斑狼疮患者中,使用99mTc标记的N-乙基马来酰亚胺(NEM)损伤红细胞获得了骨髓与脾脏的可视化图像。这种现象在自体和同源红细胞中均可产生。将该患者的NEM损伤红细胞给予一名健康患者后,未产生骨髓的可视化图像。在一系列接受标记和损伤红细胞注射的健康人和患有不同疾病的患者中未观察到这种现象,且迄今为止文献中也未见报道。

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Unusual bone marrow visualization with 99mTc-damaged erythrocytes.99mTc 标记的损伤红细胞显示出异常的骨髓影像。
Eur J Nucl Med. 1982;7(5):240-1. doi: 10.1007/BF00256473.
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本文引用的文献

1
THE SEQUESTRATION OF NEM-TREATED RED CELLS IN NORMAL AND ABNORMAL SUBJECTS: A TEST OF SPLENIC UPTAKE FUNCTION.正常及异常受试者中经NEM处理的红细胞的隔离:脾脏摄取功能的一项测试
J Lab Clin Med. 1965 Jun;65:951-66.
2
Technetium-labeled red blood cells.
J Nucl Med. 1971 Jan;12(1):22-4.
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Evaluation of Technetium-labeled red cells for determination of red cell volume in man.
J Nucl Med. 1972 Oct;13(10):760-2.
4
Splenic imaging with 99mTc-labeled erythrocytes: a comparative study of cell-damaging methods.
J Nucl Med. 1976 Dec;17(12):1038-43.
5
Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus.系统性红斑狼疮中网状内皮系统Fc受体功能缺陷
N Engl J Med. 1979 Mar 8;300(10):518-23. doi: 10.1056/NEJM197903083001002.
6
Defective reticuloendothelial system function in rheumatoid arthritis.类风湿关节炎中网状内皮系统功能缺陷
Lancet. 1979 Jun 23;1(8130):1311-4. doi: 10.1016/s0140-6736(79)91947-0.