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儿童呼吸系统疾病与家庭环境。II. 呼吸系统疾病与二氧化氮、温度和相对湿度之间的关联。

Childhood respiratory illness and the home environment. II. Association between respiratory illness and nitrogen dioxide, temperature and relative humidity.

作者信息

Melia R J, Florey C du V, Morris R W, Goldstein B D, John H H, Clark D, Craighead I B, Mackinlay J C

出版信息

Int J Epidemiol. 1982 Jun;11(2):164-9. doi: 10.1093/ije/11.2.164.

DOI:10.1093/ije/11.2.164
PMID:7095966
Abstract

The relation of respiratory illness to nitrogen dioxide (NO2), temperature and relative humidity in homes with a gas cooker was investigated in five and six year old children living in an urban area of the northern England. NO2 was measured for one week in the child's bedroom and living room of each home, and temperature and relative humidity were measured in the bedroom only. Information on respiratory conditions experienced by the child and characteristics of the home was collected in a self-administered questionnaire completed by the child's mother. Access was gained to 183 homes (54.3% of 337) where only gas was used for cooking. Complete information was obtained for 179 (93.7%) of 191 children who lived in the 183 homes. After allowing for the effects of age, sex, social class, and number of cigarette smokers in the home and temperature or relative humidity, no statistically significant relation was found between the prevalence of having one or more respiratory conditions and weekly average levels of NO2 in the bedroom (range 4.7 to 160.8 ppb) or living room (range 9.0 to 292.2 ppb). However, the prevalence of having one or more respiratory conditions tended to be highest in homes with high levels of NO2 and lowest in homes with low levels, consistent with earlier findings. A significant positive association was found between the prevalence of respiratory conditions and relative humidity (p less than .05). A harmful effect on health from NO2 cannot be totally dismissed but if it exists it is weak and difficult to detect in small samples of children.

摘要

在英格兰北部城市地区,对5至6岁儿童进行了一项研究,调查使用燃气灶具家庭中呼吸系统疾病与二氧化氮(NO2)、温度和相对湿度之间的关系。在每个家庭儿童的卧室和客厅测量二氧化氮一周,仅在卧室测量温度和相对湿度。通过孩子母亲填写的自填问卷收集有关孩子经历的呼吸状况和家庭特征的信息。共有183户家庭(占337户的54.3%)仅使用燃气做饭。在这183户家庭居住的191名儿童中,有179名(93.7%)获得了完整信息。在考虑了年龄、性别、社会阶层、家中吸烟人数以及温度或相对湿度的影响后,未发现患有一种或多种呼吸系统疾病与卧室(范围为4.7至160.8 ppb)或客厅(范围为9.0至292.2 ppb)中二氧化氮的每周平均水平之间存在统计学上的显著关系。然而,患有一种或多种呼吸系统疾病的患病率在二氧化氮水平高的家庭中往往最高,在二氧化氮水平低的家庭中最低,这与早期研究结果一致。发现呼吸状况的患病率与相对湿度之间存在显著正相关(p小于0.05)。不能完全排除二氧化氮对健康的有害影响,但如果存在,这种影响较弱且在小样本儿童中难以检测到。

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