Andressen C, Henseler T
Hautarzt. 1982 Apr;33(4):214-7.
Detailed pedigrees were established in 2,035 families with psoriasis, including 30 twin pairs, and evaluated by means of computer analysis. The following results on the devolution of psoriasis were drawn: the hypotheses of the irregular dominant and the bifactorial recessive inheritance appear to be inacceptable. The findings suggest a multifactorial etiology of psoriasis with a polygenic mode of inheritance. The risk for relatives to be affected by psoriasis is calculated.
为2035个银屑病家庭建立了详细的谱系，其中包括30对双胞胎，并通过计算机分析进行评估。得出了以下关于银屑病遗传的结果：不规则显性遗传和双因子隐性遗传的假设似乎不可接受。研究结果表明银屑病具有多因素病因，遗传方式为多基因遗传。计算了亲属患银屑病的风险。
