Ormiston M C, Gear M W, Codling B W
J Clin Pathol. 1982 Jul;35(7):757-60. doi: 10.1136/jcp.35.7.757.
This paper describes a five year follow-up study of the incidence and course of gastritis affecting the antrum and body of the stomach of 50 patients, most of whom presented with non-ulcer dyspepsia and a few with peptic ulceration. We have shown that antral gastritis, like gastritis affecting the fundus, becomes more severe in a proportion of patients as time goes by. Perhaps more important is the increased severity and progression of atrophic and metaplastic change in the antrum compared with the fundus. The significance of these changes with regard to the development of peptic ulceration and malignancy is discussed.
本文描述了一项对50例患者胃窦和胃体胃炎发病率及病程的五年随访研究，其中大多数患者表现为非溃疡性消化不良，少数患者患有消化性溃疡。我们已经表明，胃窦炎与影响胃底的胃炎一样，在一部分患者中会随着时间的推移而变得更加严重。或许更重要的是，与胃底相比，胃窦萎缩和化生改变的严重程度增加且有进展。本文还讨论了这些改变对于消化性溃疡和恶性肿瘤发生的意义。
