甲型H1N1流感病毒的历史性回归及其对英国人口的影响。
The return of the historic influenza A H1N1 virus and its impact on the population of the United Kingdom.
作者信息
Chakraverty P, Cunningham P, Pereira M S
出版信息
J Hyg (Lond). 1982 Aug;89(1):89-100. doi: 10.1017/s0022172400070571.
Abstract
The epidemiology in the United Kingdom of the influenza A H1N1 subtype which returned in 1977 after an absence of 20 years in described for the four winter seasons from 1977/8 to 1980/1. The age distribution of virus isolates and the evidence for antigenic variation is presented. The impact in the susceptible age groups year by year is shown by the change in the population with specific antibody. There was the expected increase of antibody in those under the age of 21 but also evidence for a significant amount of infection or re-infection in the older adult population.
摘要
本文描述了1977/8至1980/1这四个冬季英国甲型H1N1流感亚型的流行病学情况。该亚型在消失20年后于1977年再次出现。文中呈现了病毒分离株的年龄分布以及抗原变异的证据。特定抗体人群的变化表明了该病毒每年对易感年龄组的影响。21岁以下人群的抗体出现了预期的增加，但也有证据表明老年人群中存在大量感染或再次感染的情况。
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