适应对大鼠应激性溃疡的影响。

Adaptation effects on activity-stress ulcers in rats.

作者信息

Glavin G B

出版信息

Pavlov J Biol Sci. 1982 Jan-Mar;17(1):42-4. doi: 10.1007/BF03003474.

Abstract

Rats were given either seven or 14 days of experience with either restricted feeding (2 hr/day) or activity (24 hr/day of access to activity wheels with ad libitum feeding). Animals were then subjected to the activity-stress ulcer procedure involving 1 hr/day of feeding and continuous access to running wheels. Neither experience with restricted feeding nor with activity wheels attenuated gastric ulceration, indicating that adaptation did not occur. Rats with either restricted feeding experience or activity experience died faster and exhibited more frequent and more severe stomach damage relative to nonexperienced controls.

摘要

给大鼠提供七天或十四天的受限进食（每天2小时）或活动（每天24小时可使用活动轮并随意进食）的体验。然后让动物接受活动应激性溃疡程序，包括每天1小时进食和持续使用活动轮。受限进食或活动轮体验均未减轻胃溃疡，表明未发生适应。与无经验的对照组相比，有受限进食体验或活动体验的大鼠死亡更快，且胃损伤更频繁、更严重。