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鸽饲养者肺患者的慢性气流阻塞:针对禽类抗原的IgE抗体患病率

Chronic airflow obstruction in a patient with pigeon breeder's lung: prevalence of IgE antibodies to avian antigens.

作者信息

Fairshter R D, Martinez I P, Novey H S

出版信息

Respiration. 1982;43(2):142-9. doi: 10.1159/000194477.

DOI:10.1159/000194477
PMID:7100661
Abstract

We report a case of pigeon breeder's lung in which chronic airflow obstruction and not restrictive lung disease was predominant. The patient's disease was severe enough to require hospitalizations twice to reverse respiratory failure. Helium-oxygen flow volume curves were consistent with a peripheral site of flow limitation, and immunoserological studies disclosed specific IgE as well as precipitating antibody responses to pigeon antigens. Immunological studies on 18 other patients with pigeon breeder's lung demonstrated a prevalence rate of specific IgE antibodies of 78%, a frequency not previously recognized. Exposures to avian antigens must be considered in patients with obstructive lung disease of unknown etiology.

摘要

我们报告一例鸽饲养者肺,其中以慢性气流阻塞而非限制性肺疾病为主。患者病情严重到需要两次住院以逆转呼吸衰竭。氦氧流量容积曲线与外周气流受限部位一致,免疫血清学研究显示对鸽抗原的特异性IgE以及沉淀抗体反应。对其他18例鸽饲养者肺患者的免疫学研究表明,特异性IgE抗体的患病率为78%,这一频率此前未被认识到。病因不明的阻塞性肺疾病患者必须考虑接触禽类抗原的情况。

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Chronic airflow obstruction in a patient with pigeon breeder's lung: prevalence of IgE antibodies to avian antigens.鸽饲养者肺患者的慢性气流阻塞:针对禽类抗原的IgE抗体患病率
Respiration. 1982;43(2):142-9. doi: 10.1159/000194477.
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