• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内啡肽释放:针刺镇痛的一种可能机制。

Endorphin release: a possible mechanism of acupuncture analgesia.

作者信息

Peng C H, Yang M M, Kok S H, Woo Y K

出版信息

Comp Med East West. 1978 Spring;6(1):57-60. doi: 10.1142/s0147291778000083.

DOI:10.1142/s0147291778000083
PMID:710079
Abstract

The action of acupuncture stimulation on analgesia has been investigated. The brain and serum extracts of acupunctured rabbits injected into rabbits produced a marked analgesic effect on the recipient, as shown by a great increase of their pain threshold. This effect is counteracted by a specific opiate anatagonist, naloxone. The data suggest that the release of the endogenous substances with morphine-like biological properties, endorphins, is increased by acupuncture stimulation, thus inhibiting pain perception.

摘要

针刺刺激对镇痛作用的研究已经展开。将针刺家兔的脑及血清提取物注射到家兔体内,可使受体产生显著的镇痛效果,表现为其痛阈大幅提高。这种效应可被一种特异性阿片拮抗剂纳洛酮所抵消。这些数据表明,针刺刺激可增加具有吗啡样生物学特性的内源性物质——内啡肽的释放,从而抑制痛觉。

相似文献

1
Endorphin release: a possible mechanism of acupuncture analgesia.内啡肽释放:针刺镇痛的一种可能机制。
Comp Med East West. 1978 Spring;6(1):57-60. doi: 10.1142/s0147291778000083.
2
Further study of the neurohumoral factor, endorphin, in the mechanism of acupuncture analgesia.对神经体液因子内啡肽在针刺镇痛机制中的进一步研究。
Am J Chin Med. 1979 Summer;7(2):143-8. doi: 10.1142/s0192415x79000118.
3
Effect of intracerebral microinjection of naloxone on acupuncture- and morphine-analgesia in the rabbit.
Sci Sin. 1981 Aug;24(8):1166-78.
4
Studies on the enhanced effect of acupuncture analgesia and acupuncture anesthesia by D-phenylalanine (first report)--effect on pain threshold and inhibition by naloxone.
Acupunct Electrother Res. 1988;13(2-3):87-97. doi: 10.3727/036012988816358705.
5
Naloxone fails to reverse pain thresholds elevated by acupuncture: acupuncture analgesia reconsidered.纳洛酮无法逆转针刺提高的痛阈:重新审视针刺镇痛作用
Pain. 1983 May;16(1):13-31. doi: 10.1016/0304-3959(83)90082-9.
6
The effect of hypophysectomy on acupuncture analgesia in the mouse.垂体切除对小鼠针刺镇痛的影响。
Brain Res. 1980 Nov 24;202(1):33-9. doi: 10.1016/0006-8993(80)90641-1.
7
[Analgesia by injection of morphine and antagonism of electro-acupuncture analgesia by injection of naloxone into septal area of rabbits].
Zhongguo Yao Li Xue Bao. 1982 Sep;3(3):150-4.
8
Possible involvement of opioid peptides of caudate nucleus in acupuncture analgesia.尾状核阿片肽可能参与针刺镇痛。
Pain. 1985 Sep;23(1):83-93. doi: 10.1016/0304-3959(85)90233-7.
9
Acupuncture and sensory thresholds.
Am J Chin Med. 1989;17(3-4):99-110. doi: 10.1142/S0192415X89000176.
10
Influence of naloxone on electro-acupuncture analgesia using an experimental dental pain test. Review of possible mechanisms of action.纳洛酮对采用实验性牙科疼痛测试的电针镇痛的影响。作用机制的可能综述。
Acupunct Electrother Res. 1987;12(1):5-22. doi: 10.3727/036012987816358940.

引用本文的文献

1
Effectiveness of bee venom acupuncture for patients suffering from periarthritis humeroscapularis.蜂毒针灸治疗肩周炎患者的疗效。
J Tradit Chin Med. 2023 Aug;43(4):795-800. doi: 10.19852/j.cnki.jtcm.2023.04.002.
2
Effects of acupuncture stimulation at different acupoints on formalin-induced pain in rats.不同穴位针刺刺激对大鼠福尔马林致痛的影响。
Korean J Physiol Pharmacol. 2014 Apr;18(2):121-7. doi: 10.4196/kjpp.2014.18.2.121. Epub 2014 Apr 3.
3
Effects of acupuncture in bronchial asthma: preliminary communication.
针刺疗法对支气管哮喘的作用:初步交流
J R Soc Med. 1982 Apr;75(4):245-8.
4
Minilaparotomy under acupuncture analgesia.针刺镇痛下的小切口剖腹术。
J R Soc Med. 1984 Apr;77(4):295-8. doi: 10.1177/014107688407700408.