Andersen K E
Contact Dermatitis. 1978 Aug;4(4):195-8. doi: 10.1111/j.1600-0536.1978.tb03788.x.
Toothpaste flavors are fragrance mixtures. Oil of peppermint and spearmint, carvone and anethole are ingredients with a low sensitizing potential, but they are used in almost every brand of toothpaste and caused seven cases of contact allergy in a 6-year period at Gentofte Hospital. Toothpaste reactions are rare due to several reasons; local factors in the mouth, the low sensitizing potential of the flavors generally used, and the lack of recognition. It is emphasized that the toothpaste battery for patch testing has to be relevant and changed according to the consumers' and manufacturers' taste and fashion.
牙膏的香味是香料混合物。薄荷油、留兰香油、香芹酮和茴香脑是致敏可能性较低的成分，但它们几乎用于每个品牌的牙膏中，在根措夫特医院的6年时间里引发了7例接触性过敏病例。由于多种原因，牙膏引起的反应很少见；口腔中的局部因素、通常使用的香料致敏可能性较低以及缺乏认知。需要强调的是，用于斑贴试验的牙膏组必须相关，并应根据消费者和制造商的口味及流行趋势进行更新。
