Lemire R J, Beckwith J B
Teratology. 1982 Apr;25(2):201-13. doi: 10.1002/tera.1420250209.
Skin-covered lesions in the sacrococcygeal region include an unusual array of congenital tumors and malformations. Excluding the easily recognized meningomyelocele, there are over 50 other conditions that occur, many of which seem to be important in linking the disciplines of teratology and oncology. While it is impossible to precisely determine the manner in which these arise, there is suggestive evidence that early structures incorporated within the caudal cell mass of the embryonic tail may play an important role. The present paper reviews the basis for this speculation from both the literature and a series of 136 cases.
骶尾部有皮肤覆盖的病变包括一系列不同寻常的先天性肿瘤和畸形。除了容易识别的脊髓脊膜膨出外，还有50多种其他病症，其中许多病症似乎在连接畸形学和肿瘤学学科方面具有重要意义。虽然不可能精确确定这些病症的发生方式，但有暗示性证据表明，纳入胚胎尾部尾侧细胞团的早期结构可能起重要作用。本文从文献和136例病例系列两方面综述了这一推测的依据。
