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[老年糖尿病。4. 从肾功能角度看老年长期糖尿病患者的心血管风险状况]

[Diabetes mellitus in the aged. 4. Cardiovascular risk profile of aged long term diabetics from the viewpoint of their kidney function].

作者信息

Schneider H, Pastow A

出版信息

Z Alternsforsch. 1983 Mar-Apr;38(2):113-7.

PMID:6868655
Abstract

The cardiovasculary risk profile of 138 old grown long term diabetics (mean age 71,1 years, mean duration of the disease 19,9 years) was analysed in the frame of the so called metabolic syndrome and put in relation to the corresponding value of serum creatinine. With increasing concentration of creatinine the mean value of diabetes-associated cardiovasculary risk factors grew with old age, where only the frequency of hyperuricaemia correlated positively to the creatinine level. With comparable level of uric acid in serum the part of pathological increasing of creatinine in older age was more marked distinctly than with younger long term diabetics et respective time of disease (n = 112, mean age 45,7 years, mean duration of the disease 19,6 years). 42,0 per cent of the younger and 60.9 per cent of the older long term diabetics showed increased values of serum creatinine (p less than 0,01). The reduction of the cardiovasculary risk factors should also be forced with old grown long term diabetics.

摘要

在所谓的代谢综合征框架内,对138名老年长期糖尿病患者(平均年龄71.1岁,平均病程19.9年)的心血管风险状况进行了分析,并将其与血清肌酐的相应值进行关联。随着肌酐浓度的增加,与糖尿病相关的心血管危险因素的平均值随年龄增长而增加,其中只有高尿酸血症的发生率与肌酐水平呈正相关。在血清尿酸水平相当的情况下,老年患者肌酐病理性升高的比例明显高于年轻的长期糖尿病患者及相应病程的患者(n = 112,平均年龄45.7岁,平均病程19.6年)。42.0%的年轻长期糖尿病患者和60.9%的老年长期糖尿病患者血清肌酐值升高(p小于0.01)。对于老年长期糖尿病患者,也应加强心血管危险因素的控制。

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