[Diabetes mellitus in the aged. 4. Cardiovascular risk profile of aged long term diabetics from the viewpoint of their kidney function].

The cardiovasculary risk profile of 138 old grown long term diabetics (mean age 71,1 years, mean duration of the disease 19,9 years) was analysed in the frame of the so called metabolic syndrome and put in relation to the corresponding value of serum creatinine. With increasing concentration of creatinine the mean value of diabetes-associated cardiovasculary risk factors grew with old age, where only the frequency of hyperuricaemia correlated positively to the creatinine level. With comparable level of uric acid in serum the part of pathological increasing of creatinine in older age was more marked distinctly than with younger long term diabetics et respective time of disease (n = 112, mean age 45,7 years, mean duration of the disease 19,6 years). 42,0 per cent of the younger and 60.9 per cent of the older long term diabetics showed increased values of serum creatinine (p less than 0,01). The reduction of the cardiovasculary risk factors should also be forced with old grown long term diabetics.