Frithz G
Am Heart J. 1982 Aug;104(2 Pt 2):413-6. doi: 10.1016/0002-8703(82)90131-4.
Administration of a once-daily dosage of pindolol seems to be a simple and effective way to treat mild to moderate hypertension and one that produces relatively few side effects. In most cases, gradual titration of the drug seems unnecessary and the optimum dose can be given initially without increasing the risk of side effects. Thus, a simpler regimen can be instituted which may encourage patient compliance--a factor of great importance in view of the long duration of the therapy.
每日服用一次吲哚洛尔似乎是治疗轻至中度高血压的一种简单有效的方法,且副作用相对较少。在大多数情况下,似乎无需逐步滴定药物,初始即可给予最佳剂量而不会增加副作用风险。因此,可以制定一种更简单的治疗方案,这可能会提高患者的依从性——鉴于治疗时间长,这是一个非常重要的因素。