使用简单分光光度法对唾液和血清中扑热息痛水平的比较研究。
A comparative study of saliva and serum paracetamol levels using a simple spectrophotometric method.
作者信息
Adithan C, Thangam J
出版信息
Br J Clin Pharmacol. 1982 Jul;14(1):107-9. doi: 10.1111/j.1365-2125.1982.tb04944.x.
Abstract
The relationship between saliva and serum paracetamol levels was investigated in ten healthy male volunteers. The salivary and serum paracetamol levels showed significant correlation with each other. The salivary and serum paracetamol concentration ratio was highly dependent on sampling time. The salivary and serum paracetamol half-lives showed significant correlation with each other while the area under curve of paracetamol concentration in saliva and serum failed to show significant correlation.
摘要
在10名健康男性志愿者中研究了唾液和血清中对乙酰氨基酚水平之间的关系。唾液和血清中对乙酰氨基酚水平之间显示出显著相关性。唾液与血清中对乙酰氨基酚浓度比高度依赖于采样时间。唾液和血清中对乙酰氨基酚的半衰期之间显示出显著相关性，而唾液和血清中对乙酰氨基酚浓度曲线下面积未显示出显著相关性。
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本文引用的文献
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Therapeutic drug monitoring in saliva.唾液中的治疗药物监测。
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