Harzmann R, Bichler K H, Kieninger G, Haumer M, Helmbrecht J, Hiller E, Neugebauer W
Eur Urol. 1978;4(5):374-8. doi: 10.1159/000473997.
In view of the known risks in homologous blood transfusions, the procedures for transfusion of endogenous blood are gaining increasing importance. Using this fact as a basis, the feasibility of direct intraoperative autotransfusion in the area of urology was investigated. 6 mongrel dogs received blood-urine autotransfusions after cystotomy and cavotomy (n = 2) as well as after left-side nephrotomy (n = 4). Coagulation and hemolysis parameters were examined 1, 2, 24 h and 7 days after the autotransfusion, and showed transitory pathological changes which were, without exception, reversible within 7 days. Clinical effects were not observed. On the basis of favorable experience, the intraoperative, machine autotransfusion was also used clinically for renal traumas (n = 13), urinary bladder traumas (n = 4) and nephrotomies (n = 3). Postoperative checks showed pathological changes in the hemolysis and coagulation values only during the first 3 postoperative days. The blood-urine autotransfusion was well tolerated without exception. Indications and contraindications for direct intraoperative autotransfusions in the area of urological operations are discussed.
鉴于同种异体输血存在已知风险，自体输血程序的重要性日益凸显。基于这一事实，研究了泌尿外科领域直接术中自体输血的可行性。6只杂种犬在膀胱切开术和剖腹术（n = 2）以及左侧肾切开术后（n = 4）接受了血尿自体输血。在自体输血后1、2、24小时和7天检查凝血和溶血参数，结果显示有短暂的病理变化，但无一例外在7天内均可逆转。未观察到临床效果。基于良好的经验，术中机器自体输血也被临床用于肾外伤（n = 13）、膀胱外伤（n = 4）和肾切开术（n = 3）。术后检查仅在前3天显示溶血和凝血值有病理变化。血尿自体输血均耐受性良好。文中讨论了泌尿外科手术领域直接术中自体输血的适应证和禁忌证。
