Klassen G A, Armour J A
Can J Physiol Pharmacol. 1982 May;60(5):698-706. doi: 10.1139/y82-095.
Intramyocardial, ventricular, aortic, and central and peripheral coronary artery as well as peripheral and central coronary venous pressures were measured simultaneously in dog hearts. A gradient of coronary vascular pressures was detected and quantitated. Stellate stimulation increased all pressures. Isoproterenol induced outflow tract obstructions so that aortic and central coronary artery pressures were unchanged while the other pressures increased. Vagal stimulation dissociated the intramyocardial venous pressure relationship in as much as arterial pressures decreased while epicardial coronary venous pressure was increased. These data suggest that coronary venous pressure in response to sympathetic stimulation increases as intramyocardial pressure increases. However, vagal stimulation permits a dissociation of these effects suggesting that coronary venous pressure regulation is complex.
在犬心脏中同时测量心肌内、心室、主动脉、冠状动脉中央和外周以及冠状静脉中央和外周压力。检测并量化了冠状血管压力梯度。星状神经节刺激使所有压力升高。异丙肾上腺素引起流出道梗阻，导致主动脉和冠状动脉中央压力不变，而其他压力升高。迷走神经刺激使心肌内静脉压力关系分离，因为动脉压力降低而心外膜冠状静脉压力升高。这些数据表明，交感神经刺激时，随着心肌内压力升高，冠状静脉压力升高。然而，迷走神经刺激使这些效应分离，表明冠状静脉压力调节是复杂的。
