Bodensteiner D C, Skikne B
Cancer. 1982 Sep 15;50(6):1181-4. doi: 10.1002/1097-0142(19820915)50:6<1181::aid-cncr2820500625>3.0.co;2-p.
A 58-year-old man with mycosis fungoides developed headache, back pain, and dorsal column signs. A diagnosis of central nervous system (CNS) involvement by mycosis fungoides was made on examination of his spinal fluid. In this patient, cranial and local radiotherapy and aggressive treatment with intrathecal methotrexate cleared the leukemic cells from his CNS, and maintenance therapy with intrathecal methotrexate has resulted in an 18-month remission.
一名58岁的蕈样肉芽肿患者出现头痛、背痛和脊髓后索体征。通过对其脑脊液检查，诊断为蕈样肉芽肿累及中枢神经系统（CNS）。在该患者中，头颅和局部放疗以及鞘内注射甲氨蝶呤的积极治疗清除了其CNS中的白血病细胞，鞘内注射甲氨蝶呤维持治疗已使其缓解达18个月。
