[糖尿病的眼部表现：285例]

[Ocular manifestations of diabetes: 285 cases].

作者信息

Zghal-Mokni Imen, Nacef Leila, Letaief Imène, Mahjoub Sonia, Bouguila Hédi, Blouza Samira, Jeddi Amel, Ayed Saïda

机构信息

Institut Hédi Raies d'ophtalmologie de Tunis.

出版信息

Tunis Med. 2008 Nov;86(11):1004-7.

PMID:19213494

Abstract

BACKGROUND

Diabetes is one of the principal cause of blindness in adults. The aim of the study is to evaluate the frequency of ocular complications and risk factors of diabetes. It's a multicentric prospective study on a representative sample of 285 diabetics.

METHODS

We performed a general and an ophthalmologic exam for all patients with retinal angiography and appropriate laboratory tests. Chi 2, Fisher, Mann and Whitney tests were used as statistical methods.

RESULTS

Diabetic retinopathy was observed in 45,2% of patients, cataract in 22%, glaucoma in 5%. Diabetic retinopathy frequency rises especially with duration of diabetes and bad glycaemic control. Blindness related to diabetic retinopathy was observed in 6,25% and visual deficiency in 12,5%. The authors compared their results with literature data. They emphasize on the great value of regular better glycaemic control and other associated metabolic disorders.

CONCLUSION

We concluded that a regular ophthalmologic follow up is necessary for early diabetic retinopathy detection and treatment.

摘要

背景

糖尿病是成年人失明的主要原因之一。本研究的目的是评估糖尿病眼部并发症的发生率及危险因素。这是一项针对285名糖尿病患者的代表性样本进行的多中心前瞻性研究。

方法

我们对所有患者进行了全面检查和眼科检查，包括视网膜血管造影及适当的实验室检查。采用卡方检验、费舍尔检验、曼-惠特尼检验作为统计方法。

结果

45.2%的患者出现糖尿病视网膜病变，22%的患者出现白内障，5%的患者出现青光眼。糖尿病视网膜病变的发生率尤其随着糖尿病病程和血糖控制不佳而升高。6.25%的患者因糖尿病视网膜病变导致失明，12.5%的患者存在视力缺陷。作者将他们的结果与文献数据进行了比较。他们强调了定期更好地控制血糖及其他相关代谢紊乱的重要价值。