Hansen W E, Maurer H, Haberland H
Hepatogastroenterology. 1982 Jun;29(3):108-10.
Sham-feeding is believed to induce only a vagal stimulus. In the present investigation its effect on gallbladder volume and bile acid circulation was studied. In 8 out of 9 persons we observed a decrease in gallbladder volume from 20.1 +/- 2.4 ml to 15.4 +/- 2.2 ml. After 150 min, serum bile acids had increased from initially 2.0 +/- 0.3 mumoles/l to 2.3 +/- 0.4 mumoles/l. In 10 persons given a liquid test meal, there was a decrease in gallbladder volume from 18.3 +/- 2.7 ml to 5.2 +/- 0.7 ml. Bile acids rose from 2.6 +/- 0.3 mumoles/l to 4.1 +/- 0.5 mumoles/l after 90 min. The response after the test meal was thus more enhanced and faster. It is concluded that: 1. Vagal stimulation from the oral mucosa by sham-feeding can induce evacuation of the gallbladder and enterohepatic circulation of bile. 2. Under normal circumstances this mechanism is probably of minor importance.
假饲被认为仅诱发迷走神经刺激。在本研究中，研究了其对胆囊容积和胆汁酸循环的影响。在9人中的8人身上，我们观察到胆囊容积从20.1±2.4毫升降至15.4±2.2毫升。150分钟后，血清胆汁酸从最初的2.0±0.3微摩尔/升升至2.3±0.4微摩尔/升。在10名给予液体试验餐的人身上，胆囊容积从18.3±2.7毫升降至5.2±0.7毫升。90分钟后胆汁酸从2.6±0.3微摩尔/升升至4.1±0.5微摩尔/升。因此，试验餐后的反应更强烈且更快。得出以下结论：1. 通过假饲对口腔黏膜的迷走神经刺激可诱发胆囊排空和胆汁的肠肝循环。2. 在正常情况下，该机制可能不太重要。
