人类精子使仓鼠卵子受精与其他精液参数的关系。

Fertilization of hamster ova by human spermatozoa in relation to other semen parameters.

作者信息

Cohen J, Mooyaart M, Vreeburg J T, Zeilmaker G H

出版信息

Int J Androl. 1982 Apr;5(2):210-24. doi: 10.1111/j.1365-2605.1982.tb00250.x.

DOI:10.1111/j.1365-2605.1982.tb00250.x

Abstract

Different indices of the zona-free hamster ovum test system were interrelated. High correlations were found between the fertilization percentage and the average number of penetrated spermatozoa/ovum (r = 0.99) and between the fertilization percentage and the number of spermatozoa attached to the ova surfaces (r = 0.72). Fertilization percentages from 63 subfertile patients were correlated with different semen factors assessed by multiple exposure photography (MEP). Low correlations were found between sperm concentration and fertilization percentage (r = 0.29) and between fertilization percentage and motile sperm count (r = 0.33). Spermatozoa progressing with high average velocity had low fertilization rates compared to specimen with moderate average velocity. Effects of sperm washing on the in vitro fertilizing capacity were studied in a group of 40 subfertile men. The fertilization percentages of 8 specimens--with visual seminal plasma abnormalities--increased significantly when immediate dilution of semen was applied.

摘要

无透明带仓鼠卵试验系统的不同指标相互关联。受精率与平均穿透精子数/卵子数之间存在高度相关性（r = 0.99），受精率与附着在卵子表面的精子数之间也存在高度相关性（r = 0.72）。63例亚生育患者的受精率与通过多次曝光摄影（MEP）评估的不同精液因素相关。精子浓度与受精率之间的相关性较低（r = 0.29），受精率与活动精子计数之间的相关性也较低（r = 0.33）。与平均速度适中的标本相比，平均速度高的精子受精率较低。在一组40例亚生育男性中研究了精子洗涤对体外受精能力的影响。当立即稀释精液时，8份有明显精浆异常标本的受精率显著提高。