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对B-DNA纤维左手双螺旋模型的批判性分析。

A critical analysis of a left-handed double helix model for B-DNA fibers.

作者信息

Albiser G, Premilat S

出版信息

Nucleic Acids Res. 1982 Jul 10;10(13):4027-34. doi: 10.1093/nar/10.13.4027.

Abstract

A search for a left-handed double helix model for B-DNA fibers has been undertaken. The model has to present good stereochemistry and also to be in agreement with X-ray and infrared data. Dihedral angles as well as atomic coordinates and calculated intensities curves are given for the best model obtained. Comparison with experimental results shows that this model must be rejected as a candidate for the representation of B-DNA fibers.

摘要

人们已经着手寻找一种用于B - DNA纤维的左手双螺旋模型。该模型必须具有良好的立体化学性质,并且要与X射线和红外数据相符。对于所获得的最佳模型,给出了二面角、原子坐标以及计算强度曲线。与实验结果的比较表明,作为B - DNA纤维表示的候选模型,该模型必须被摒弃。

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