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与纤维X射线和红外二色性一致的A-DNA和B-DNA构象。

Conformations of A-DNA and B-DNA in agreement with fiber X-ray and infrared dichroism.

作者信息

Premilat S, Albiser G

出版信息

Nucleic Acids Res. 1983 Mar 25;11(6):1897-908. doi: 10.1093/nar/11.6.1897.

Abstract

Two right handed double helices are proposed as models for DNA fibers in respectively the A and the B form. The present conformations have geometrical parameters which agree very well with fiber X-ray and the orientation of their phosphate groups is in good accordance with infrared dichroïsm measurements. Dihedral angles and complete sets of atomic coordinates are given together with stereo-views and curves of the calculated diffracted intensities. Results are compared with experimental data and with preceding DNA models.

摘要

提出了两个右手双螺旋结构作为分别处于A 型和B 型的DNA 纤维模型。目前的构象具有与纤维X 射线非常吻合的几何参数,并且其磷酸基团的取向与红外二色性测量结果高度一致。给出了二面角和完整的原子坐标集,以及立体视图和计算出的衍射强度曲线。将结果与实验数据以及之前的DNA 模型进行了比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f493/325843/eaea7c054813/nar00351-0272-a.jpg

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