Rossi P, Galli E, Cantani A, Perlini R, Sellitto F, Businco L
Ann Allergy. 1982 Sep;49(3):159-64.
This report is of seven-year-old girl with a lifelong history of severe eczema, intestinal features of food allergy, recurrent respiratory tract infections, chronic bilateral keratitis and mucocutaneous candidiasis. Immunological tests showed high serum IgE levels, with specific IgE antibodies to cow's milk and egg white, defective PMN chemotaxis and a marked defect in both the function and number of T-lymphocytes. On a cow's milk-free and egg-free diet the eczema subsided and the respiratory infections improved. A partial correction of the immunodeficiency was also observed. The relationships between the immune system and atopy are discussed.
本报告讲述了一名七岁女童，她有严重湿疹的终生病史、食物过敏的肠道症状、反复的呼吸道感染、慢性双侧角膜炎和黏膜皮肤念珠菌病。免疫测试显示血清IgE水平升高，对牛奶和蛋清有特异性IgE抗体，PMN趋化功能缺陷以及T淋巴细胞功能和数量均有明显缺陷。采用无牛奶和无鸡蛋饮食后，湿疹消退，呼吸道感染改善。还观察到免疫缺陷有部分纠正。文中讨论了免疫系统与特应性之间的关系。
