Goldstone T P, Crompton M
Biochem J. 1982 Apr 15;204(1):369-71. doi: 10.1042/bj2040369.
The existence of a Na(+)-dependent mechanism for Ca(2+) efflux from isolated rat liver mitochondria was confirmed. The activity of this system is decreased by 60% in mitochondria isolated from perfused livers. The Na(+)-dependent activity is fully restored by infusion of either 1mum-adrenaline or 1mum-isoprenaline, but the alpha-adrenergic agonist phenylephrine is ineffective.
已证实存在一种从分离的大鼠肝线粒体中排出钙离子的钠离子依赖机制。该系统的活性在从灌注肝脏分离的线粒体中降低了60%。通过注入1μM肾上腺素或1μM异丙肾上腺素可使钠离子依赖活性完全恢复，但α-肾上腺素能激动剂去氧肾上腺素无效。
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