Bharadvaj B K, Mabon R F, Giddens D P
J Biomech. 1982;15(5):349-62. doi: 10.1016/0021-9290(82)90057-4.
The geometry of a typical adult human carotid bifurcation, complete with the sinus, was established from a study of a large number of angiograms. A rigid model was constructed from glass and investigations were performed under steady flow conditions using flow visualization techniques over a range of upstream Reynolds numbers and flow division ratios through the branches representative of physiologic conditions expected in the human vasculature. The study reveals a complex flow field in which secondary flows play an important role. The separation regions occurring at the outer corners of the branching are also subjected to much higher shear stress. Comparison with pathologic data on localization of atherosclerotic lesions indicates that zones susceptible to disease experience low or oscillatory shear stress while regions subject to higher shear are free of deposits.
通过对大量血管造影照片的研究，确定了具有窦的典型成年人类颈动脉分叉的几何形状。用玻璃构建了一个刚性模型，并在稳定流动条件下，使用流动可视化技术，在一系列代表人体血管系统预期生理状况的上游雷诺数和分支流量分配比下进行了研究。该研究揭示了一个复杂的流场，其中二次流起着重要作用。分支外角处出现的分离区域也承受着高得多的剪切应力。与动脉粥样硬化病变定位的病理数据比较表明，易患疾病的区域经历低剪切应力或振荡剪切应力，而承受较高剪切力的区域没有沉积物。
